2024 Top2b

Top2b

Author: iiqc

August undefined, 2024

Web2. nov 2024 · TOP2A is essential for cell division, is highly expressed during mitosis, and is required for mitotic chromosome condensation and segregation ( 13 – 16 ). Genetic … Web17. feb 2024 · Description: Homo sapiens DNA topoisomerase II beta (TOP2B), transcript variant 1, mRNA. (from RefSeq NM_001330700) RefSeq Summary (NM_001330700): This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as …

Top2B在蒽环类药物治疗的儿童急性白血病中的表达及心脏毒性的 …

http://www.cancerindex.org/geneweb/TOP2B.htm Web6. nov 2024 · Topoisomerase 2 beta (Top2b) is an important enzyme in transcriptional activation of some inducible genes through transient double-stranded DNA breakage events around promoter regions. We created a conditional, tissue-specific, inducible Top2b knockout mice in the heart. Serendipitously, echocardiographic parameters and more … sign in to bing account

The chemotherapeutic CX-5461 primarily targets TOP2B and

WebKontakt. Top 2B GmbH. Flecken 4. 6023 Rothenburg. T 041 281 07 02. F 041 280 07 08. mail (at)top2b.ch. Alle mit * markierten Felder sind Pflichtfelder! Name*. Web15. okt 2024 · AbstractPurpose:. The epigenetic mechanisms involved in transcriptional regulation leading to malignant phenotype in gliomas remains poorly understood. … sign in to bigpond email online

Calcineurin dephosphorylates topoisomerase IIβ and regulates the …

Topoisomerase IIα represses transcription by enforcing promoter ...

Web17. jan 2014 · Summary. Topoisomerase IIbeta (Top2b) is an enzyme that modulates DNA supercoiling by catalyzing the passage of DNA duplexes through one another. It is ubiquitously expressed in postmitotic cells and known to function during the development of neuromuscular junctions in the diaphragm and the proper formation of laminar structure … DNA topoisomerase 2-beta is an enzyme that in humans is encoded by the TOP2B gene. sign into bigpond accountWeb12. apr 2024 · Original Concentration: 120µg/mL. Applications: Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.) Predicted isoelectric point: 8.7. Predicted Molecular Mass: 27.5kDa. Accurate Molecular Mass: 30kDa as determined by SDS-PAGE reducing conditions. the quest for dean bridgman conner

"Web18. jan 2024 · Only ten patients with TOP2B-mediated immunodeficiency have been published in the medical literature since 2001; all of them had dominant-negative mutations affecting TOPRIM, the DNA gating domain of TOP2B [4,5,6,7,8,9]. Delays in diagnosis are common in this disease which results in remarkably associated morbidity. " - Top2b

Top2b

Web9. nov 2024 · TOP2B expression was also associated with MYCN expression when we conditioned on del(p3) and age-at-diagnosis using multivariate linear regression (P = 3.3 × … Webnpm1 parp1 ncl hspa4 top2b tle1 nono rad50 : parp1 src polr2a camk2d hes1 nono crebbp kat2b : copb2 cope copz1 arf1 arcn1 copa copb1 copg1 : cog7 cog2 cog1 cog3 cog8 cog4 cog5 cog6 : cog7 cog2 cog1 cog3 cog8 cog4 cog5 cog6 : eif2s1 xrcc6 xrcc5 eif2s2 eif2s3 prkdc ilf2 ilf3 : tbkbp1 hsp90aa1 hsp90ab1 traf2 cdc37 tank azi2 tbk1

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Web这说明，pol ii的停顿与释放是形成内源dsbs的决定因素，并且这一过程主要由top2b的剪切作用来实现。那么，对于这种内源产生的dsbs，细胞又会如何应对呢？研究人员通过检测经典ddr通路中的γ-h2ax信号，发现不同于 … WebTamoxifen诱导Cre-ERT2小鼠使用指南. Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。. 查看. 【小鼠大学问】基因工程小鼠的命名规则. 常见的 ...

Web13. júl 2024 · Notably, TOP2B null SH-SY5Y cells upregulated mesenchymal markers vimentin (VIM) and fibronectin (FN1) and components of the NOTCH signalling pathway. Enrichment analysis and comparison with the transcription profiles of other neuroblastoma-derived cell lines supported the conclusion that TOP2B is required to fully maintain the … http://www.cnreagent.com/show1001180/product_94100.html

http://www.top2b.ch/ Web13. apr 2024 · A representative western blot image of TOP2B and TOP2A levels in wild-type (WT) and TOP2B −/− RPE-1 cells is shown (right) (n = 3). (D) c-FOS mRNA levels in cells …

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Web21. mar 2024 · An important paralog of this gene is TOP2B. UniProtKB/Swiss-Prot Summary for TOP2A Gene Key decatenating enzyme that alters DNA topology by binding to two … the quest for kadan lost ark maxrollWeb12. apr 2024 · Original Concentration: 200µg/mL. Applications: Positive Control; Immunogen; SDS-PAGE; WB. (May be suitable for use in other assays to be determined by the end user.) Predicted isoelectric point: 6.1. Predicted Molecular Mass: 46.3kDa. Accurate Molecular Mass: 46kDa as determined by SDS-PAGE reducing conditions. sign in to bing business accountWebTOP2A. （topoisomerase (DNA) II alpha）. 这个基因编码一种DNA拓扑异构酶，这种酶在转录过程中控制和改变DNA的拓扑状态。. 这种核酶参与诸如染色体凝聚、染色单体分离以 … sign into bing accountWebAll lanes : Anti-Topoisomerase II beta/TOP2B antibody (ab125297) Lane 1 : Wild-type HEK-293T cell lysate Lane 2 : TOP2B knockout HEK-293T cell lysate Lysates/proteins at 40 µg … sign in to bingeWeb31. jan 2002 · Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, … sign in to bing chat with work accounthttp://www.bioon.com.cn/doc/showarticle.asp?newsid=112623 sign in to binge accountWeb4. apr 2024 · TOP2B DNA topoisomerase II beta. TOP2B. DNA topoisomerase II beta. Gene ID: 7155, updated on 4-Apr-2024. Gene type: protein coding. Also known as: BILU; TOPIIB; … sign in to bing