Lycopene toxicity
Web3 dec. 2015 · Lycopene is an ingredient found in a variety of supplements and vitamins. Generic Name. Lycopene. DrugBank Accession Number. DB11231. Background. Lycopene is a naturally occuring red carotenoid pigment that is responsible in red to pink colors seen in tomatoes, pink grapefruit, and other foods 1. Having a chemical formula of … Web20 oct. 2024 · Lycopene is a red carotenoid pigment with strong antioxidant activity. Saccharomyces cerevisiae is considered a promising host to produce lycopene, but lycopene toxicity is one of the limiting factors for high-level production. In this study, we used heterologous lycopene biosynthesis genes crtE and crtI from Xanthophyllomyces …
Lycopene toxicity
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WebLycopene: Hepatoprotective and Antioxidant Effects toward Bisphenol A-Induced Toxicity in Female Wistar Rats. Bisphenol A (BPA)—an endocrine disruptor xenoestrogen—is widely spread in the environment. Lycopene (LYC) is an antioxidant phytochemical carotenoid. The hereby study was designed to verify the deleterious effect … Web24 oct. 2024 · Cyclophosphamide (CYC) is the first-line chemotherapy drug for cancer in clinical practice, and its intestinal toxicity seriously affects the treatment effect and prognosis of patients. Lycopene (LP) is the main pigment of ripe tomatoes and has strong antioxidant activity. However, the mechanism by which LP prevents CYC-induced …
Web7 nov. 2024 · In summary, the nanoemulsion loaded with lycopene purified from red guava did not cause physiological alterations that could indicate in vivo toxicity. The toxicity of nanoparticles is a critical factor for the biological application of drug delivery systems and needs to be comprehensively explored prior to further in vivo studies. Absorption of lycopene requires that it be combined with bile salts and fat to form micelles. Intestinal absorption of lycopene is enhanced by the presence of fat and by cooking. Lycopene dietary supplements (in oil) may be more efficiently absorbed than lycopene from food. Lycopene is not an essential nutrient for humans, but is commonly found in the diet mainly from dishes prepared from tomatoes. The median and 99th percentile of dietary lycopene intake hav…
WebEpidemiological studies show that drug-induced nephrotoxicity is the third most common cause of acute kidney disease, 1 and it is one of the major contributing factors to chronic kidney disease ... Wu XI, Wang WE, Wang XI, Ma J. Quercetin with lycopene modulates enzymic antioxidant genes pathway in isoproterenol cardiotoxicity in rats. ... WebIn addition to its antioxidant properties, lycopene shows an array of biological effects including cardioprotective, anti-inflammatory, antimutagenic and anticarcinogenic …
WebSpecial Issue: Novel Formulation Strategies for the Delivery of Natural Therapeutic Agents emphasizing the active role of natural products extracted from plants, animals or microbial origin
WebLycopene: Hepatoprotective and Antioxidant Effects toward Bisphenol A-Induced Toxicity in Female Wistar Rats. Bisphenol A (BPA)—an endocrine disruptor xenoestrogen—is … laplace transform of fWeb24 oct. 2024 · Cyclophosphamide (CYC) is the first-line chemotherapy drug for cancer in clinical practice, and its intestinal toxicity seriously affects the treatment effect and … hendo relishWebFluoride intoxication is associated with oxidative stress and altered anti-oxidant defense mechanism. Lycopene is a lipid-soluble powerful anti-oxidant that scavenges free radicals and ROS. Objective: This study was extended to investigate lycopene anti-oxidant efficacy in different organs of fluoride-intoxicated rats. hen do sashes ebayWebThese products were evaluated for toxicological and behavioral effects during a 13-week oral dosing study with male and female Wistar rats. Doses of 0, 500, 1500 and 3000 … hendo roofing and repairWebLycopene, as a one of the most potent antioxidant, is found in fruits and vegetables. High-intake of lycopene has been shown to be effective in decreasing the risk of both natural … laplace transform of piecewiseWeb5 aug. 2024 · Lycopene has high solubility and can pass through the testicular barrier, suggesting a potentially helpful treatment for testicular toxicity associated with oxidative stress. Cytochrome P450 2E1 is the … laplace transform of odeMice were given a single dose of 3 g/kg crystalline (e.g., unformulated) lycopene by various routes of administration. There were no adverse effects when mice were given lycopene orally or intraperitoneally. There was, however, a transient decrease in body tone when lycopene was given by subcutaneous injection … Vedeți mai multe Christian and co-workers (7) conducted a study on rats and rabbits in which 0, 0.5, 1.5, or 3 g/(kg · d) of formulated lycopene was given during gestation. There was no effect of … Vedeți mai multe A series of studies evaluated the hepatic uptake of lycopene (1). When rats were fed up to 20 mg/(kg · d) of lycopene as either formulated lycopene or tomato concentrate, the highest concentrations were found in … Vedeți mai multe A series of studies was conducted by Roche Vitamins in which the mutagenicity of crystalline and formulated lycopene was evaluated using the Ames test with several strains of bacteria (1). There was no mutagenic … Vedeți mai multe Studies have been conducted in rats using [14C]lycopene for evaluating the absorption and metabolism of lycopene (1,8). Only ∼7–10% of lycopene was absorbed, with roughly half being excreted in urine and … Vedeți mai multe laplace transform of sawtooth wave