Hoxb7cre
WebDownload scientific diagram Hoxb7cre:Itga6 flox/flox mice have increased injury after UUO (A-F) Morphology of H&E stained kidney sections from Itga6 flox/flox (A, C, E) and … WebIn Hoxb7cre Tg/+ /Fgfr2 Lox/Lox tissues, we detected linear Fgfr2 expression only in stromal cells on either side of the nephric duct and ureteric bud epithelia (Fig. 6c).
Hoxb7cre
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Web1 jan. 2024 · Based on the finding that the collecting system of the Hoxb7cre:Itga6 flox/flox and Hoxb7cre:Itgb4 flox/flox mice developed dysplastic papillae over time, we tested the hypothesis that α6-containing integrins play a critical role in maintaining kidney structure following injury by subjecting them to unilateral ureteric obstruction (UUO). ). These … Web14 apr. 2024 · Author summary Primary cilia are sensory organelles found on most cells and contain specific receptors that detect extracellular stimuli. Defects in trafficking receptors …
Web18 apr. 2008 · HoxB7Cre knockouts displayed a wide range of kidney abnormal - ities ranging from bilateral agenesis to apparently normal-sized kid … Web1 mrt. 2024 · Hoxb7Cre Rosa nT-nG/nT-nG generated nuclear GFP + kidney tubules and yielded living GFP +, calcein AM + cells upon FACS (Supplemental Figure 3). Compared …
Web25 mrt. 2015 · The collecting system of the kidney develops from the ureteric bud (UB), which undergoes branching morphogenesis, a process regulated by multiple factors, … WebUse {[Name]} for functional genomics research and drug discovery study.
Web12 okt. 2016 · Background Mutations in the tumor suppressor gene von Hippel-Lindau (VHL) underlie a hereditary cancer syndrome—VHL disease—and are also frequently observed …
Web13 mei 2024 · Tissue-specific bulk RNA sequencing of MAPK/ERK-deficient renal progenitor populations. A Whole mount image example of a mouse kidney expressing HoxB7Cre … flagstar cutting employee 2022Web1 mrt. 2024 · Hoxb7Cre Rosa nT-nG/nT-nG generated nuclear GFP + kidney tubules and yielded living GFP +, calcein AM + cells upon FACS (Supplemental Figure 3). Compared with unsorted single cells prepared from the whole kidney, Hoxb7Cre Rosa nT-nG/nT-nG enriched collecting duct principal cell genes and depleted TALH, proximal tubule, and … flagstar dupont road fort wayneWebOur Hoxb7cre line has been shown to drive efficient deletion of Fgfr1, Fgfr2 and Frs2a in the UB (Sims-Lucas et al., 2009b; Zhao et al., 2004). For this study, Lox/LoxFgfr2[gift from Dr David Ornitz, Washington University, St Louis, MO, USA (Yu et al., 2003)] were bred with Frs2a Lox/Loxmice (Lin et al., 2007) to produce Fgfr2Lox/LoxFrs2a mice. canon pixma printer scanner software downloadWebFrs2α Hoxb7cre/ureteric bud Mild renal hypoplasia with less ureteric branching and fewer nephrons [7] Fgfr2/ Frs2α Hoxb7cre/ureteric bud Embryonic kidneys with thin ureteric … flagstar earnings releaseWebinactivation of Ptch1 using Hoxb7Cre, resulting in constitu-tive Hh signaling within the ureteric lineage, causes renal hy-poplasia. In these mutant mice, abnormal tip … canon pixma printer softwareWebHoxb7Cre driven loss of Mdm4 in the Ub lineage (Ub Mdm4-/-) disrupts branching morphogenesis and triggers UB cell apoptosis. Ub Mdm4-/-kidneys exhibit abnormally dilated Ub tips while the medulla is hypoplastic. These structural alterations result in secondary depletion of nephron progenitors and nascent nephrons. flagstar escrow addressWebTg(Hoxb7-cre)13Amc - Embryo-other Recombinase Activity Detail Allele Information Tissue Information Images Recombinase Activity References flagstar escrow refund